Endocrine Abstracts

Graves’ disease is a common autoimmune disorder with autoimmunity against the TSH-receptor being a central pathogenetic element. The disease may present with a number of clinical manifestations, among which hyperthyroidism caused by TSH-receptor stimulating antibodies is the most prevalent. The disease is common in all adult ages and affects women 4–5 times more often than men.In many countries the preferred initial therapy of the hyperthyroidi...

Iodine is an essential part of thyroid hormones, and many processes in the thyroid gland adapt to changes in iodine supply. Still, abnormalities in iodine intake are of major importance for the occurrence of thyroid diseases. Historically, the intake of iodine from food and beverage has been low in large parts of the world. Depending on the level of insufficiency, this has been associated with disturbed reproduction, developmental brain damage, and a high occurrence of goitre ...

Both humic substances (HS) and iodine may influence the thyroid gland. Tap water is a major source of iodine intake in some areas, where iodine has been shown to be bound in HS.We investigated tap water and old subjects from two areas with and without iodine bound in HS in tap water, to assess their importance for urinary iodine excretion and for the thyroid. Analysis of tap water, measurement of iodine in urine and thyrotropin (TSH), thyroid peroxidase ...